Title
Maize Carotenoid Gene Locus Mining Based on Conditional Gaussian Bayesian Network
Abstract
How to mine the gene locus for maize carotenoid components is an important research problem in biology study. Along with the rapid development of high-throughput biotechnologies, we have produced a large number of maize multi-omics data, including genome, transcriptome, metabolome, phenotype, etc. How to conjointly analyze these continuous and discrete data, and thus to mine the genetic loci that control the maize carotenoid components have a very important biological significance. In this work, we use the conditional Gaussian Bayesian network learning method to construct the network of maize gene, SNP locus and carotenoid components, aim to get the possible significant loci about four reported genes for the carotenoid component traits. The method is validated using the multi-omics data of maize global germplasm collection with 368 elite inbred lines. Four algorithms are used to do the comparison, and experiment results show the method can mine the effective locus for the phenotype traits. It is concluded that the conditional Gaussian Bayesian network learning method is an effective way of analyzing multi-omics data conjointly, mining the possible gene locus for maize carotenoid component traits, and thus to provide genetic resources and useful information for molecular breeding of maize.
Year
DOI
Venue
2020
10.1109/ACCESS.2020.2966590
IEEE ACCESS
Keywords
DocType
Volume
Gene locus mining,maize,conditional Gaussian Bayesian network,carotenoid components
Journal
8
ISSN
Citations 
PageRank 
2169-3536
0
0.34
References 
Authors
0
6
Name
Order
Citations
PageRank
Jianxiao Liu100.34
Yu Kang200.34
Kai Liu300.34
Xuan Yang400.34
Menghai Sun500.34
Junfan Hu600.34