Title
Publishing reproducible dynamic kinetic models
Abstract
Publishing repeatable and reproducible computational models is a crucial aspect of the scientific method in computational biology and one that is often forgotten in the rush to publish. The pressures of academic life and the lack of any reward system at institutions, granting agencies and journals means that publishing reproducible science is often either non-existent or, at best, presented in the form of an incomplete description. In the article, we will focus on repeatability and reproducibility in the systems biology field where a great many published models cannot be reproduced and in many cases even repeated. This review describes the current landscape of software tooling, model repositories, model standards and best practices for publishing repeatable and reproducible kinetic models. The review also discusses possible future remedies including working more closely with journals to help reviewers and editors ensure that published kinetic models are at minimum, repeatable. Contact: hsauro@uw.edu
Year
DOI
Venue
2021
10.1093/bib/bbaa152
BRIEFINGS IN BIOINFORMATICS
Keywords
DocType
Volume
systems biology, kinetic modeling, SBML, standards, reproducibility
Journal
22
Issue
ISSN
Citations 
3
1467-5463
0
PageRank 
References 
Authors
0.34
0
3
Name
Order
Citations
PageRank
Veronica Porubsky100.34
Lucian Smith2588.79
Herbert M Sauro31330203.16