Title
i6mA-word2vec: A Newly Model Which Used Distributed Features for Predicting DNA N6-Methyladenine Sites in Genomes
Abstract
DNA N6 methyladenine (6mA) is a widely studied and widespread epigenetic modification, which plays a vital role in cell growth and development. 6mA is present in many biological cellular processes, such as the regulation of gene expression and the rule of cross dialogue between transposon and histone modification. Therefore, in some biological research, the prediction of the 6mA site is very significant. Unfortunately, the existing biological experimental methods are expensive both in time and money. And they cannot meet the needs of existing research. So it is high time to develop a targeted and efficient computing model. Consequently, this paper proposes an intelligent and efficient calculation model i6mA-word2vec for the discrimination of 6mA sites. In our work, we use word2vec from the field of natural language processing to carry out distributed feature encoding. The word2vec model automatically represents the target class topic. Then, the extracted feature space was sent into the convolutional neural network as prediction input. The experimental prediction results show that our computational model has better performance.
Year
DOI
Venue
2022
10.1007/978-3-031-13829-4_58
INTELLIGENT COMPUTING THEORIES AND APPLICATION, ICIC 2022, PT II
Keywords
DocType
Volume
Methylation of DNA N6-methyladenine, word2vec, Deep learning
Conference
13394
ISSN
Citations 
PageRank 
0302-9743
0
0.34
References 
Authors
0
6
Name
Order
Citations
PageRank
Wenzhen Fu100.34
Yixin Zhong200.34
Baitong Chen301.35
Yi Cao401.01
Jiazi Chen501.35
Hanhan Cong601.35